As a new puppy parent, feeling excited and overwhelmed is natural.

Puppies bring joy, companionship, and endless cuddles—but they also come with responsibilities, including vaccinations.

Vaccinations are vital to keeping your furry friend healthy and safe, and if you’re wondering, “How much does a puppy and dog vaccination cost?” you’re in the right place.

First-Year Puppy Vaccination Costs

The first year of a puppy’s life requires several rounds of vaccinations. Here’s a typical breakdown of costs:

VaccineFrequencyAverage Cost (2025)

• DHPP (Distemper) - 3 doses - $55–$70/per dose
• RabiesOnce - yearly - $55–$70
• Bordetella - Annually - $55–$70
• Leptospirosis - Annually - $55–$70
• Lyme Disease - Annually - $55–$70

Most veterinarians bundle these vaccinations into packages to make them more affordable.

A full set of core vaccines for your puppy can range between $75 and $150, excluding exam fees.

Additional Costs

• Exam Fees: Most vets charge $40–$95 per visit.
• Deworming: Typically $20–$150 - Depending on size
• Microchipping: Optional but recommended, costing around $25–$80.

Costs for Adult Dog Vaccinations

After the first year, your dog will need booster shots to maintain immunity.

The costs are lower than the initial puppy vaccinations and are typically spaced 1–3 years apart.

Here’s what you can expect:

Vaccine Frequency & Average Cost (2025)

• DHPP - (Booster) - Every 1–3 years - $55–$70
• Rabies - (Booster) - Every 1–3 years - $55–$70
• Bordetella - Annually - $55–$70
• Leptospirosis - Annually - $55–$70

Vaccinations are your puppy’s first line of defense against life-threatening diseases.

Puppies are especially vulnerable to illnesses like parvovirus and distemper, which can spread quickly and be fatal without proper prevention.

Core vaccines, such as those protecting against rabies and distemper, are necessary for all dogs.

Not only do they safeguard your pet’s health, but some, like the rabies vaccine, are legally required in most areas.

Keeping your dog’s vaccinations up to date will help protect other pets and people in your community.

At what age do you stop vaccinating your dog?

Dogs typically continue receiving vaccinations throughout their lives, although the frequency may decrease as they age.

Senior dogs still need protection, especially against rabies and other diseases. Always consult your vet for tailored advice.

What is the 7-in-1 vaccine for dogs?

The 7-in-1 vaccine protects against seven diseases: distemper, adenovirus, hepatitis, parainfluenza, parvovirus, leptospirosis (two strains), and coronavirus.

Covering multiple illnesses in a single shot is convenient and commonly given to puppies and dogs.

Core Vaccines

Core vaccines are essential for every dog, regardless of their lifestyle or location. These include:

• DHPP: Protects against distemper, hepatitis, parainfluenza, and parvovirus.
• DA2PPC: Protects against both canine adenovirus types 1 & 2, also known as canine hepatitis.
• Rabies: Protects against the deadly rabies virus that is transmissible to humans.

Lifestyle vaccines often include:

• Bordetella: Protects against kennel cough, which is common in dogs that frequent daycare or boarding facilities.
• Leptospirosis: Protects against a bacterial infection that spreads through water or soil contaminated by animal urine.
• Lyme Disease: Recommended for dogs in areas with a high tick population.
• Canine Influenza: Recommended for high-risk dogs or dogs that travel often.

Low-Cost Vaccination Options

If the cost of vaccinations feels daunting, there are several affordable options available:

Community Clinics

Local animal shelters and rescue organizations often host low-cost vaccination clinics.

These events provide core vaccines at a fraction of the price charged by private veterinarians.

Check with your local humane society for upcoming dates.

Mobile Vet Clinics

Retail chains like Petco and PetSmart frequently host mobile vet clinics.

These offer convenient, affordable vaccine packages for both puppies and adult dogs.

Pet Insurance

Many pet insurance plans cover vaccinations as part of their wellness packages.

While you’ll pay a monthly premium, the savings on routine care can make it worthwhile.

Tips to Save on Puppy & Dog Vaccinations

• Bundle Services: Many vets offer discounted packages that include multiple vaccinations, exams, and preventative care.
• Compare Prices: Call different clinics and mobile vet services to find the best rates.
• Utilize Wellness Plans: Some veterinary practices offer wellness plans with monthly payments that cover vaccinations and exams.
• Combine Visits: Schedule vaccinations alongside regular checkups to save on additional exam fees.